The objective of oncogenetics, a medical discipline, is to:

• understand genetic predisposition to cancers
• care for persons at risk.

Genetic predispositions are often associated with a family history of cancer. However, cancers are very frequent and family histories exist, so a family history of cancer is not synonymous with a genetic predisposition.

The purpose of a genetic consultation is to determine the share of family history and possible predisposition.

Genetic tests, stills seldom practiced, sometimes confirm a hereditary origin. If an alteration is identified in a family, it can be sought in its relations. This makes it possible to reassure those having no predisposition and following up those at risk.

Oncology or cancerology, is the specific medical study, diagnostic and treatment of cancers.

Osteosarcoma is a primary bone cancer: it is not a metastasis. It is characterised by the abnormal production of bone cells (osteoblasts) from the bone marrow, inside the bone or the membrane that surrounds the bone.

This rare cancer generally occurs in children, adolescents and young adults (10-20 years old), and frequently in the femur, tibia, humerus and knee. It causes pain and swelling. Standard treatment combines surgery and chemotherapy.